Wavefront-guided custom ablation for myopia using the NIDEK NAVEX laser system.

PURPOSE To determine the predictability, efficacy, safety, and stability of LASIK using custom ablation with the NIDEK Advanced Vision Excimer Laser System (NAVEX). METHODS One hundred twenty eyes underwent LASIK for myopia using the OPDCAT algorithm. Refractive outcomes and the change in higher order aberrations, coma, and spherical aberrations were analyzed. Postoperative follow-up ranged from 6 to 18 months. RESULTS Mean postoperative spherical equivalent refraction was -0.05 diopters (D) (range: -0.92 to +0.88 D). Uncorrected visual acuity was 1 or better in 109 (91%) eyes and 1.2 or better in 47 (39%) eyes. Postoperative spherical equivalent refraction was within +/- 0.50 D of intended correction in 110 (92%) eyes. Fifty-two (43%) eyes gained 1 or more lines of best spectacle-corrected visual acuity (BSCVA), and no eyes lost more than 1 line of BSCVA. Higher order aberrations root-mean-square increased by 0.053 microm postoperatively. Patients with preoperative higher order aberrations > or = 0.3 microm were less likely to have induced higher order aberrations. CONCLUSIONS Wavefront-guided OPDCAT treatments with the NIDEK NAVEX system for myopia are safe and effective with excellent visual acuity and refractive outcomes. Eyes with > or = 0.3 microm of higher order aberrations preoperatively will benefit more from OPDCAT treatment than eyes with a smaller amount of higher order aberrations.